ea0022oc1.3 | Diabetes and obesity | ECE2010
Vcelak Josef
, Seda Ondrej
, Vankova Marketa
, Lukasova Petra
, Vrbikova Jana
, Tremblay Johanne
, Bendlova Bela
, Hamet Pavel
The identification of genomic determinants responsible for common multifactorial diseases like type 2 diabetes mellitus (T2DM) is facilitated in large families from relatively genetically-isolated populations and can extend results from GWS based on a case–control cohort to detect rare alleles with strong effects. In order to search for sequence variants conferring risk of T2DM we previously conducted a genome-wide linkage study in 108 French–Canadian families from t...